"The 40-Year-Old Virgin" star is going to lead the yet-untitled film.
The Hollywood supercouple have reportedly tied the knot.
WATCH: Jimmy Kimmel wrote some "Friends" fan fiction and got Jennifer Aniston, Courteney Cox and Lisa Kudrow in on the act.
Grab your proton pack,"Ghostbusters" is hitting the big screen in a limited re-release. Who you gonna call?